Why you should be taking Gluco-Gel

Gelatin and collagen were plentiful in our ancestral diet, however fairly scarce in the modern diet plan….

This scarcity a major problem.

Here’s an explanation of what gelatin and collagen are, the difference between them, and why they’re essential, plus simple methods to get more of them in your own diet plan.

Get Your Gelatin and Collagen the Easy Way…

Gelatin and Collagen: Missing Pieces in the Modern Diet

The story of gelatin in fact starts with a protein called collagen. Collagen is the most essential protein in connective tissue, skin, and bones; you really have more collagen in your body than any other kind of protein. Destruction or absence of collagen can trigger issues from skin wrinkles to osteoporosis.

In food, collagen is discovered mostly in the “odd bits” and harder cuts of beef that contain a great deal of connective tissue. You may acknowledge these as the parts of the animals that our ancestors consumed, but we generally throw them away today.

Gelatin comes into this since people seldom consume skin and tendons raw; they cook them. Heating the collagen during cooking transforms it into gelatin. Gelatin is the prepared form of collagen– it’s the form of it we can consume to gain the advantageous amino acids in the collagen without having to sit down to a lovely plate of raw tendons for dinner.

So far, so easy, however there’s another distinction to make. Cooking collagen-rich foods extracts gelatin, but more extensive processing can also develop a somewhat different compound called collagen hydrolysate.

Collagen Hydrolysate vs. Gelatin

Collagen hydrolysate (which is the very same thing as hydrolyzed collagen) is not exactly the same thing as gelatin. In the hydrolyzed type, the collagen is processed more intensively, which separates the proteins into smaller pieces. They both have the exact same amino acids, but differing chemical properties.

The benefits of collagen are mainly from the amino acids, and you break down both gelatin and hydrolyzed collagen into the same amino acids in your digestion system anyway, so in regards to health benefits, hydrolyzed collagen and gelatin are comparable. But on the other hand, some individuals with might find the hydrosylate much easier to digest, and they do have culinary differences in regards to how you’ll use them.

Science of Health Benefits of Collagen and Gelatin –

Enhancing Antioxidant Capacity

Hydrolized collagen (CH) has effecient antioxidant activity as demonstrated by in vitro assays [10,11]. CH intake also increases the activities of antioxidant enzymes in body, including SOD, GSH-Px and CAT [3,12]. Nuclear factor E2-related factor 2 (Nrf2)-antioxidant response element (ARE) pathway plays a central role in regulating antioxidant enzymes. Therefore, we speculate that CH exerts its antioxidant effect in a direct and/or indirect manner. More work is needed to investigate the effect of CH on Nrf2-ARE signaling.

Anti aging effect

Anti aging effect of CH has been widely investigated in several animal models, including photo aged model, chronologically aged model and acetone-induced dry skin model [3,12-15]. General beneficial effects, including increasing skin hydration, decreasing the formation of deep wrinkles and improving skin elasticity, are also observed in clinical trials after taking 10g of CH once a day for more than 6 weeks [16]. It should be noted that anti aging effect of CH is more obvious on women aged more than 30 years. Mechanisms underlying the beneficial effects may be involved in the dual effects of CH on skin collagen synthesis and degradation, as previous study reported [13].

Bone and Joint Health

Anti osteoporotic and anti osteoarthritis effects of CH have been reviewed by Daneault et al. [17] and Porfírio et al. [18]. Daily doses equivalent to 12g of CH significantly promotes an improvement in the symptoms of osteoarthritis and osteoporosis [18]. Combined CH with other nutritional ingredients has received much interest. It has been reported that combined oral administration of CH with calcium and vitamin D has better effects on bone health than alone administration of CH or calcium and vitamin D [19-21]. Future studies are needed to determine the optimal form and optimal dose of CH.

Enhancing wound healing

Oral administration of marine CH is reported to enhance cutaneous wound healing and angiogenesis in rats [22-23]. In addition to elevated VEGF and FGF-2 expression, the effect of CH on fibroblast may be one of the mechanisms underlying enhanced wound healing, as previous study reported that Pro-Hyp, a collagen-derived dipeptide, exerts a chemotactic action on fibroblast and stimulates fibroblast proliferation [8].

Anti-inflammatory effect

Glycine is one of the major structural units of collagen, accounting for one-third of the amino acids. CH has the ability to reduce inflammatory responses [24,25]. This effect may be constituted by inhibiting the production of pro-inflammatory cytokine via glycine-gated chloride channels (GlyR).

Antitumor effect

Liang et al. reported CH intake inhibited spontaneous tumor incidence and increase life spanin sprague-dawley (SD) rats [26]. Our previous study found that CH intake inhibited platelet.

Collagen is necessary for skin and bone health– supplements are sold for whatever from wrinkles to osteoporosis. As well as supplying the crucial amino acids for collagen shops in your body, gelatin and hydrolyzed collagen likewise have gut-healing advantages that may be even more important from a health point of view.

Again, it’s important to point out that due to the fact that the majority of the health advantages of collagen/gelatin come from the amino acids, it’s likely that for most people, the benefits will be the very same whether you’re getting hydrolyzed collagen or gelatin.

There’s some evidence that hydrolyzed collagen supplements improve arthritis pain and normally benefit bone and joint health.

Gelatin may assist stabilize gut hormonal agents in individuals with weight problems.

Gelatin and collagen are both also fantastic for your gut– they help heal digestive tract permeability (“dripping gut”) and bring back the regular mucosal layer in the gut.

Gelatin particularly likewise has some fantastic cooking uses– do not discount the benefits of making healthy food tastier. For something, gelatin makes your pan sauces remarkable.

The food science nerds at Serious Eats have taken this one on: the reason why standard stock makes a better pan sauce than broth in a can is that the conventional variation has more gelatin. Sure, you could doctor up your store-bought broth with extra gelatin powder to re-create the impact, however why would you do that when you could just utilize the genuine thing?

How to Get More Gelatin and Collagen in Your Life


No one eats raw collagen– in theory you could, but you ‘d have to sit around gnawing on raw animal tendons and bones. However you can include more gelatin and hydrolyzed collagen to your diet rather easily.

For the Traditionalists: Gelatin from Animal Foods

Homemade bone broth is a cost effective and delicious source of gelatin.

You can’t get hydrolyzed collagen from home cooking unless your cooking area includes an entire chemistry laboratory. However considering that they’re most likely equivalent for most people, getting more gelatin is most likely to give you the same outcomes. Here’s how to get it:

Bone broth is the primary, and easy to get gelatin source. If it becomes chicken or beef Jell-O when you stick it in the fridge, then you understand it’s full of gelatin (here are some tips for making that occur). Drink it plain or use it in soups.

Roasts with great deals of connective tissue (think chuck roast and comparable cuts) will also produce meat and broth loaded with gelatin if you prepare them slowly in a crock pot, thanks to the breakdown of collagen in the meat.

Non-Traditional but Tasty

If you’re not insistent about getting your gelatin directly from the source, hydrolyzed collagen and gelatin powder are available at almost all supermarket (generally in the baking aisle, beside the Jell-O or with the pie filling). Purified protein-in-a-can will not have any of the other great things you receive from meat and broth, but it’s definitely convenient and you can do all examples with it …

Gelatin: make your own gummy candies, puddings, or gelatin desserts.
Gelatin: add it to sauces and soups to thicken them.
Collagen: stir it into your coffee or tea, or perhaps just a glass of water. Theoretically, you can do this with gelatin too, however most people discover the texture of coffee + gelatin to be extremely off-putting.

Alternative: add to shakes. Some individuals like the gelatin texture in shakes; other individuals would rather just supplement with collagen.

Summing it Up

There’s an old piece of advice to “consume what ails you”– whatever part of your body is offering you difficulty, eat that part of the animal and you’ll feel much better.

It does not operate in every case, and it’s not a terribly sound clinical principle, however in the case of gelatin and collagen, it basically holds true: consuming gelatin derived from the skin and bones of animals can help your own skin and bone health.

Gelatin and collagen also have outstanding gut-healing advantages, and they’re very simple to get into your diet. Get more gelatin from bone broth or slow-cooked roasts, or just take a faster way and purchase them in pure form to contribute to whatever you like. It’s not difficult at all, and it’s another way to get a little extra gelatin and collagen in your diet.


  1. Ali ME, Sultana S, Hamid SBA, Hossain MM, YehyaWA, et al. (2016) Gelatin Controversies in Food, Pharmaceuticals and Personal Care Products: Authentication Methods, Current Status and Future Challenges. Crit Rev Food SciNutr 29: 1-7.
    18.Porfírio E, Fanaro GB (2016) Collagen supplementation as a complementary therapy for the prevention and treatment of osteoporosis and osteoarthritis: a systematic review. RevistaBrasileira de Geriatria e Gerontologia 19: 153-164.
  2. Oesser S, Adam M, Babel W, Seifert J (1999) Oral administration of 14C labeled gelatin hydrolysate leads to an accumulation of radioactivity in cartilage of mice (C57/BL). J Nutr 129(10): 1891-1895.
    19.Liu J, Wang Y, Song S, Wang X, QinY, et al. (2015) Combined oral administration of bovine collagen peptides with calcium citrate inhibits bone loss in ovariectomized rats. PloS one 10(10): e0135019.
  3. Song H, Meng M, Cheng X, Li B, Wang C (2017) The effect of collagen hydrolysates from silver carp (Hypophthalmichthys molitrix) skin on UV-induced photo aging in mice: molecular weight affects skin repair. Food Funct 8(4): 1538-1546.
  4. Elam ML, Johnson SA, Hooshmand S, Feresin RG, Payton ME, et al. (2015) A calcium-collagen chelate dietary supplement attenuates bone loss in postmenopausal women with osteopenia: a randomized controlled trial. J Med Food 18(3): 324-331.
  5. Brandsch M (2013) Drug transport via the intestinal peptide transporter PepT1. Curr Opin Pharmacol 13(6): 881-887.
  6. Hooshmand S, Elam ML, Browne J, Campbell SC, Payton ME (2013) Evidence for bone reversal properties of a calcium-collagen chelate, a novel dietary supplement. J Food NutrDisor 2: 1.
  7. Wang L, Wang Q, Liang Q, He Y, Wang Z, et al. (2015) Determination of bioavailability and identification of collagen peptide in blood after oral ingestion of gelatin. J Sci Food Agric 95(13): 2712-2717.
  8. Zhang Z, Wang J, Ding Y, Dai X, Li Y (2011) Oral administration of marine collagen peptides from Chum Salmon skin enhances cutaneous wound healing and angiogenesis in rats. J Sci Food Agric 91(12): 2173-2179.
  9. Taga Y, Kusubata M, Ogawa-Goto K, Hattori S (2016) Efficient absorption of X-hydroxyproline (Hyp)-Gly after oral administration of a novel gelatin hydrolysate prepared using ginger protease. J Agric Food Chem 64(14): 2962-2970.
  10. Wang J, Xu M, Liang R, Zhao M, Zhang Z, et al. (2015) Oral administration of marine collagen peptides prepared from chum salmon (Oncorhynchus keta) improves wound healing following cesarean section in rats. Food Nutr Res 59: 26411.
  11. Yazaki M, ItoY, Yamada M, Goulas S, Teramoto S, et al. (2017) Oral Ingestion of Collagen Hydrolysate Leads to the Transportation of Highly Concentrated Gly-Pro-Hyp and Its Hydrolyzed Form of Pro-Hyp into the Bloodstream and Skin. J Agric Food Chem 65: 2315-2322.
  12. Hartog A, Cozijnsen M, de Vrij G, Garssen J (2013) Collagen hydrolysate inhibits zymosan-induced inflammation. ExpBiol Med 238(7): 798-802.
  13. Ohara H, Ichikawa S, Matsumoto H, Akiyama M, Fujimoto N, et al. (2010) Collagen-derived dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibroblasts. J Dermatol 37(4): 330-338.
  14. Zhang Y, Kouguchi T, Shimizu K, Sato M, Takahata Y, et al. (2010) Chicken collagen hydrolysate reduces proinflammatory cytokine production in C57BL/6.KOR-ApoEshl mice. J NutrSciVitaminol 56(3): 208-210.
  15. Hatanaka T, Kawakami K, Uraji M (2014) Inhibitory effect ofcollagen- derived tripeptides on dipeptidylpeptidase-IV activity. JEnzyme InhibMedChem 29(6): 823-828.
  16. Liang J, Pei XR, Wang N, Zhang ZF, Wang JB, et al. (2010) Marine collagen peptides prepared from chum salmon (Oncorhynchus keta) skin extend the life span and inhibit spontaneous tumor incidence in sprague- dawley rats. J Med Food 13(4): 757-770.
  17. Alemán A, Giménez B, Pérez-Santin E, Gómez-Guillén MC, Montero P (2011) Contribution of Leu and Hyp residues to antioxidant and ACE- inhibitory activities of peptide sequences isolated from squid gelatin hydrolysate. Food Chem 125: 334-341.
  18. Song H, Zhang L, Luo Y, Zhang S, Li B (2017) Effects of Collagen Peptides Intake on Skin Aging and Platelet Release in Chronologically Aged Mice Revealed by Cytokine Array Analysis.
    11.Nakchum L, Kim SM (2016) Preparation of squid skin collagen hydrolysate as an antihyaluronidase, antityrosinase, and antioxidant agent. Prep BiochemBiotechnol 46(2): 123-130.
  19. Lee JK, Jeon JK, Byun HG (2014) Antihypertensive effect of novel angiotensin I converting enzyme inhibitory peptide from chum salmon (Oncorhynchus keta) skin in spontaneously hypertensive rats. J Funct Foods 27: 381-389.
  20. Wang Z, Wang Q, Wang L, Xu W, He Y, et al. (2017) Improvement of skin condition by oral administration of collagen hydrolysates in chronologically aged mice. J Sci Food Agric 97(3): 2721-2726.
  21. Kouguchi T, Ohmori T, Shimizu M, Takahata Y, Maeyama Y, et al. (2013) Effects of a chicken collagen hydrolysate on the circulation system in subjects with mild hypertension or high-normal blood pressure. BiosciBiotechnolBiochem 77 (4): 691-696.
  22. Liang J, Pei X, Zhang Z, Wang N, Wang J, et al. (2010) The Protective Effects of Long-Term Oral Administration of Marine Collagen Hydrolysate from Chum Salmon on Collagen Matrix Homeostasis in the Chronological Aged Skin of Sprague-Dawley Male Rats. J Food Sci 75(8): 230-238.
  23. Tang L, Sakai Y, Ueda Y, Katsuda S (2015) Effects of oral administration of tripeptides derived from type I collagen (collagen tripeptide) on atherosclerosis development in hypercholesterolemic rabbits. J BiosciBioeng 119(5): 558-563.
  24. Fan J, Zhuang Y, Li B (2013) Effects of collagen and collagen hydrolysate from jellyfish umbrella on histological and immunity changes of mice photoaging. Nutrients 5: 223-233.
  25. Lee EJ, Hur J, Ham SA, Jo Y, Lee S, et al. (2017) Fish collagen peptide inhibits the adipogenic differentiation of preadipocytes and ameliorates obesity in high fat diet-fed mice. Int J BiolMacromol 104: 281-286.
  26. Okawa T, Yamaguchi Y, Takada S, Sakai Y, Numata N, et al. (2012) Oral administration of collagen tripeptide improves drynessand pruritus in the acetone-induced dry skin model. J DermatolSci 66(2): 136-143.
    32.Tometsuka C, Koyama YI, Ishijima T, Toyoda T, Teranishi M, et al. (2017) Collagen peptide ingestion alters lipid metabolism-related gene expression and the unfolded protein response in mouse liver. Br J Nutr 117(1): 1-11.
    16.Sibilla S, Godfrey M, Brewer S, Budh-Raja A,Genovese L (2015) An overview of the beneficial effects of hydrolysed collagen as a nutraceutical on skin properties: Scientific background and clinical studies. Open Nutraceuticals J 8: 29-42.
    33.Zhang R, ChenJ, Jiang X, Yin L, Zhang X (2016) Antioxidant and hypoglycaemic effects of tilapia skin collagen peptide in mice. Int J Food Sci 51(10): 2157-2163.
    17.Daneault A, Prawitt J, Fabien Soulé V, Coxam V, Wittrant Y (2017) Biological effect of hydrolyzed collagen on bone metabolism. Crit Rev Food Sci Nutr 57(9): 1922-1937.
  27. Iba Y, Yokoi K, Eitoku I, Goto M, Koizumi S, et al. (2016) Oral Administration of Collagen Hydrolysates Improves Glucose Tolerance in Normal Mice Through GLP-1-Dependent and GLP-1-Independent Mechanisms. J Med Food 19: 836-843.